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This white paper provides general information for using EMC Data Domain deduplication storage to back up VMs using VMware Consolidated Backup (VCB) with VMware Infrastructure 3(VI3). Topics include an overview of V13 components and various methods of backing up data in disk (VMDK) images and guest OS files for discrete recovery – either locally or remotely in a DR site. The central focus is on selecting the backup approach best suited to meet specific needs, and by extensions, how Data Domain systems can be leveraged to assist online restoration and replication to a DR site.